The Carpal tunnel, which is located inside the wrist, is a space where the median nerve and tendons pass through. The inner pressure of the tunnel can increase as a result of various diseases (such as rheumatoid arthritis), injuries, fluid retention during pregnancy, overuse or repetitive hand motion. Increased inner pressure causes compression on the nerve which results in symptoms such as numbness, pain, tingling and weakening of the grip. The disease which shows up with these symptoms is called the Carpal Tunnel Syndrome.